RAF Typhoon FGR4s have conducted a mission with France's air force in a combined operation against an subterranean weapons facility in Syria used by the Islamic State group (IS), according to the UK's MoD.
The site, pinpointed through surveillance, was assessed as storing arms and explosives, the statement said, and was located in mountainous terrain just above the historic site of Palmyra in Syria's central region.
"The RAF jets employed precision-guided Paveway IV munitions to hit a several approach shafts leading to the facility... early reports suggest the strike was effective," officials stated.
There was no sign of any harm to civilians in the attack late on Saturday and every plane involved returned to base without incident, the ministry further stated.
The Typhoon FGR4s were backed up by a Voyager refuelling tanker.
IS - referred to as the so-called Islamic State - enforced jihadist rule over parts of Iraq and Syria until 2019.
"This strike underscores the UK's leading role, and determination to stand shoulder to shoulder with allied nations, to stamp out any re-emergence of IS and their harmful and extremist ideologies in the region," Britain's Defence Chief the minister remarked.
UK warplanes have conducted patrols over Syrian airspace to "deter any attempted resurgence" of the group following its defeat at the climactic battle in Baghuz in the year 2019, the ministry said.
"I want to thank all the members of our armed forces who took part in this operation for their expertise and their valour," the Defence Secretary added. "Including them were a great many UK service members on duty over the holidays. This operation, to remove terrorist threats who pose a risk to our way of life, shows how our armed forces are always on standby, throughout the year, keeping Britain secure at home and powerful internationally."
In December, the US military conducted what it called a "large-scale strike" targeting Islamic State objectives in the country, subsequent to an ambush claimed the lives of two American soldiers and a civilian linguist in the Palmyra area.
The United Nations estimates Daesh still boasts roughly 5-7 thousand fighters in Syria and Iraq.